Researcher Database
244 researchers found.
Name | Site | Program | Email / Phone | |
---|---|---|---|---|
Prof. Dr. Björn Scheffler | Essen/Dusseldorf | EOM | b.scheffler@dkfz-heidelberg.de | Details |
Dr. med. Florian Scherer | Freiburg | MDEB | florian.scherer@uniklinik-freiburg.de | Details |
Prof. Dr. Oliver Schilling | Freiburg | ROI, MDEB | oliver.schilling@uniklinik-freiburg.de | Details |
Prof. Dr. Peter Schirmacher | Heidelberg | CCP, MDEB | Peter.Schirmacher@med.uni-heidelberg.de | Details |
Prof. Dr. Heinz-Peter Schlemmer | Heidelberg | ROI | h.schlemmer@dkfz-heidelberg.de | Details |
Prof. Dr. Roland Schmid | Munich | EOM | rolandm.schmid@mri.tum.de | Details |
Dr. Andreas Schmidt | Freiburg | ROI | andreas.schmidt@uniklinik-freiburg.de | Details |
Prof. Dr. Marc Schmidt-Supprian | Munich | EOM, MTT | marc.supprian@tum.de | Details |
Prof. Dr. Marc Schmitz | Dresden | CI | marc.schmitz@tu-dresden.de | Details |
Prof. Dr. Evelin Schröck | Dresden | MDEB, CI | evelin.schrock@tu-dresden.de | Details |
Prof. Dr. Roland Schüle | Freiburg | EOM, MDEB | roland.schuele@uniklinik-freiburg.de | Details |
Prof. Dr. Martin Schuler | Essen/Dusseldorf | MTT | martin.schuler@uk-essen.de | Details |
Prof. Dr. Johannes Schulte | Berlin | EOM | johannes.schulte@charite.de | Details |
Prof. Dr. Klaus Schulze-Osthoff | Tubingen | EOM, MTT | kso@uni-tuebingen.de | Details |
Prof. Dr. Matthias Schwab | Tubingen | MDEB | matthias.schwab@ikp-stuttgart.de | Details |
Prof. Dr. Harald Schwalbe | Frankfurt/Mainz | MTT | schwalbe@nmr.uni-frankfurt.de | Details |
PD Dr. med. Stefan Schwartz | Berlin | stefan.schwartz@dkfz-heidelberg.de / +49 30 8445 4022 | Details | |
Prof. Dr. Christine Sers | Berlin | EOM, MDEB | christine.sers@charite.de | Details |
Prof. Dr. Hubert Serve | Frankfurt/Mainz | CCP, EOM, MTT | serve@em.uni-frankfurt.de | Details |
Dr. Lisa Sevenich | Frankfurt/Mainz | ROI, CI | Sevenich@gsh.uni-frankfurt.de | Details |
Prof. Dr. Britta Siegmund | Berlin | EOM | britta.siegmund@charite.de | Details |
Prof. Dr. Jens Siveke | Essen/Dusseldorf | MTT | J.Siveke@dkfz.de / +49 201 723 3704 | Details |
Prof. Dr. Julia Skokowa | Tubingen | EOM | julia.skokowa@med.uni-tuebingen.de | Details |
Prof. Dr. Martin Sos | Munich | EOM, CI | martin.sos@dkfz-heidelberg.de | Details |
Prof. Dr. Karsten Spiekermann | Munich | CGP, MDEB, MTT | Karsten.Spiekermann@med.uni-muenchen.de | Details |
DKTK Junior Group Leader for Cancer Systems Biology
Single-cell approaches have not only revealed a wide variety of cell states, characterized by cells exhibiting striking differences in their transcriptional profile, but have also illuminated the mechanisms underlying state transitions in health and disease. Cellular plasticity and adaptive state changes have recently emerged as a basis for therapeutic resistance in cancer, and a better understanding of how cell state transitions are regulated is critical to develop therapeutic approaches that can overcome therapy resistance.
Our research focuses on understanding the mechanisms driving non-genetic cellular heterogeneity and therapy resistance in malignancy. Using novel single-cell sequencing approaches, we seek to develop new experimental and computational strategies to define altered cell states in both, cancer and immune cells. Our aim is to leverage a data driven strategy combined with single cell genomics and systems biology to address the challenges posed by heterogeneity in cancer, and to develop new strategies to overcome it, with the aim of translating laboratory-based findings into the clinic.